@InProceedings{OliveiraPedrDias:2020:FuBLEn,
author = "Oliveira, Gabriel Bianchin de and Pedrini, Helio and Dias,
Zanoni",
affiliation = "Institute of Computing, University of Campinas, Campinas, SP,
Brazil, 13083-852 and Institute of Computing, University of
Campinas, Campinas, SP, Brazil, 13083-852 and Institute of
Computing, University of Campinas, Campinas, SP, Brazil,
13083-852",
title = "Fusion of BLAST and Ensemble of Classifiers for Protein Secondary
Structure Prediction",
booktitle = "Proceedings...",
year = "2020",
editor = "Musse, Soraia Raupp and Cesar Junior, Roberto Marcondes and
Pelechano, Nuria and Wang, Zhangyang (Atlas)",
organization = "Conference on Graphics, Patterns and Images, 33. (SIBGRAPI)",
publisher = "IEEE Computer Society",
address = "Los Alamitos",
keywords = "Protein Structure Prediction, Classifier Ensemble, Amino Acid
Sequence.",
abstract = "The prediction of protein secondary structure has great relevance
in the analysis of global protein folding. In this work, we
present a method for protein secondary structure prediction using
the fusion of BLAST and the ensemble of local and global
classifiers. We used the amino acid sequence and sequence
similarity information available in the datasets and we explored
other amino acid characteristics. In order to evaluate our method,
we used the files from PDB (only from the year 2018), as well as
CB6133 and CB513 datasets. We achieved 87.7%, 82.4% and 85.6% Q8
accuracy on PDB 2018, CB6133 and CB513 proteins using the amino
acid sequence and amino acid biological properties, 84.7% and
87.5% Q8 accuracy on CB6133 and CB513 proteins using the amino
acid sequence and similarity sequence information and 92.5% Q3
accuracy on PDB 2018 proteins using the amino acid sequence and
amino acid biological properties. Our method presented competitive
results using only BLAST and only the ensemble of classifiers. The
fusion of both approaches achieved superior results compared to
state-of-the-art approaches.",
conference-location = "Porto de Galinhas (virtual)",
conference-year = "7-10 Nov. 2020",
doi = "10.1109/SIBGRAPI51738.2020.00049",
url = "http://dx.doi.org/10.1109/SIBGRAPI51738.2020.00049",
language = "en",
ibi = "8JMKD3MGPEW34M/4395EF2",
url = "http://urlib.net/ibi/8JMKD3MGPEW34M/4395EF2",
targetfile = "PID6614063.pdf",
urlaccessdate = "2025, Mar. 15"
}