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		<identifier>8JMKD3MGPAW/3S3D9HP</identifier>
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		<site>sibgrapi.sid.inpe.br 802</site>
		<citationkey>Borges:2018:DoSaDi</citationkey>
		<author>Borges, Lucas R.,</author>
		<affiliation>Escola de Engenharia de São Carlos, EESC, USP</affiliation>
		<title>Dose Savings in Digital Breast Tomosynthesis through Image Processing</title>
		<conferencename>Conference on Graphics, Patterns and Images, 31 (SIBGRAPI)</conferencename>
		<year>2018</year>
		<editor>Ross, Arun,</editor>
		<editor>Gastal, Eduardo S. L.,</editor>
		<editor>Jorge, Joaquim A.,</editor>
		<editor>Queiroz, Ricardo L. de,</editor>
		<editor>Minetto, Rodrigo,</editor>
		<editor>Sarkar, Sudeep,</editor>
		<editor>Papa, João Paulo,</editor>
		<editor>Oliveira, Manuel M.,</editor>
		<editor>Arbeláez, Pablo,</editor>
		<editor>Mery, Domingo,</editor>
		<editor>Oliveira, Maria Cristina Ferreira de,</editor>
		<editor>Spina, Thiago Vallin,</editor>
		<editor>Mendes, Caroline Mazetto,</editor>
		<editor>Costa, Henrique Sérgio Gutierrez,</editor>
		<editor>Mejail, Marta Estela,</editor>
		<editor>Geus, Klaus de,</editor>
		<editor>Scheer, Sergio,</editor>
		<booktitle>Proceedings</booktitle>
		<date>Oct. 29 - Nov. 1, 2018</date>
		<publisheraddress>Porto Alegre</publisheraddress>
		<publisher>Sociedade Brasileira de Computação</publisher>
		<conferencelocation>Foz do Iguaçu, PR, Brazil</conferencelocation>
		<keywords>Digital breast tomosynthesis, dose reduction, image processing, denoising.</keywords>
		<abstract>In x-ray imaging, the ALARA principle defines that the x-ray radiation must be kept as low as reasonably achievable to ensure the patients safety. However, low-dose acquisitions yield images with low quality, which affect the radiologists image interpretation. Therefore, there is a compromise between image quality and radiation dose. This work proposes an image restoration framework capable of restoring low-dose acquisitions to achieve the quality of full-dose acquisitions. The contribution of the new method includes the capability of restoring images with quantum and electronic noise, pixel offset and variable detector gain. To validate the image processing chain, a simulation algorithm was proposed. The simulation generates low-dose digital breast tomosynthesis (DBT) projections, starting from full-dose images. To investigate the feasibility of reducing the radiation dose in breast cancer screening programs, a simulated pre-clinical trial was conducted using the simulation and the image processing pipeline proposed in this work. Objective and subjective results suggest that reduction of 30% - 50% in radiation dose could be achieved after the proposed image processing pipeline was applied. Thus, the image processing algorithm has the potential to decrease radiation levels in DBT, also decreasing the cancer induction risks associated with the exam.</abstract>
		<language>en</language>
		<tertiarytype>Master's or Doctoral Work</tertiarytype>
		<format>On-line</format>
		<size>118 KiB</size>
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		<targetfile>Submission_Lucas_30_07.pdf</targetfile>
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		<e-mailaddress>lucas.rodrigues.borges@usp.br</e-mailaddress>
		<usergroup>lucas.rodrigues.borges@usp.br</usergroup>
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